Table 2.
Intraepithelial TILs | ||||||
CD3 | CD8 | FoxP3 | ||||
Site | Avg. Diff. (95% CI) | p value | Avg. diff. (95% CI) | p value | Avg. diff. (95% CI) | p value |
Primaries (ovaries) | (ref) | (ref) | (ref) | (ref) | (ref) | (ref) |
Metastases | −0.07 (−0.30, 0.17) | 0.57 | −0.09 (−0.29, 0.12) | 0.40 | 0.12 (−0.14, 0.17) | 0.37 |
Significant global effects? | No, p = 0.30 | No, p = 0.35 | No, p = 0.32 | |||
Stromal TILs | ||||||
CD3 | CD8 | FoxP3 | ||||
Site | Avg. Diff. (95% CI) | p value | Avg. diff. (95% CI) | p value | Avg. diff. (95% CI) | p value |
Primaries (ovaries) | (ref) | (ref) | (ref) | (ref) | (ref) | (ref) |
Metastases | 0.41 (0.21, 0.62) | 0.020 | 0.39 (0.20, 0.57) | 0.00002 | 0.22 (0.04, 0.47) | 0.086 |
Significant global effects? | Yes, p = 0.0003 | Yes, p = 0.0001 | Yes, p = 0.0003 |