Figure 4.

Over-expression of PPARδ potentiates the differentiation response. A: Both wild type (squares) and SENSE cells (inverted triangles) were treated with increasing concentrations of PMA. Numbers of adherent cells were quantified by SYBR green staining and compared to a standard curve. B: Over-expression of PPARδ (inverted triangles) enhances the maintenance of adhesion following a single treatment with PMA when compared with the parental cell line (squares). For comparison, the compound F result (triangles; broken line) is also shown.