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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Genes Immun. 2011 Jun 9;12(7):575–581. doi: 10.1038/gene.2011.12

Figure 3. Alteration of IL10R1 expression throughout cell cycle.

Figure 3

(a) HeLa cells transfected with IL10R1-WT were treated with nocodazole for 14 h and analyzed for DNA content upon staining with propidium iodide (+noc). Non-treated cells served as a control (−noc). (b) HeLa cells transfected with IL10R1-WT were arrested in G2/M by nocodazol and further cultured with or without IL-10 for 0, 3, 6, 9, 12 and 24 hours. The percentage of cells within the G0/G1-, S-, and G2/M phase is shown. Data represent mean ± SD of three independent experiments. (c) Correlation between IL10R1 expression levels and percentage of cells within G0/G1- (r=0.534; p=0.037), S- (r=0.253; p=0.214), or G2/M phase (r=−0.443; p=0.075) are shown. MFI of IL10R1 expression are presented as the fold-change for each time point compared to t=0. Correlations (r) and significance (p) were calculated by Pearson correlation analysis.

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