Table 1.

Summary of parameters used in basal and EH conditions.

Symbol	Description	Value for basal conditions	Value for EH conditions	Unit
k1	Rate constant of diffusion of glucose and its analogs from plasma to interstitial space	0.040	0.044	ml/ml per min
ISg	Interstitial glucose concentration	5.1	3.0	mmol/ml IS space
ICg	Intracellular glucose concentration	0.050	0.135	mmol/ml IC space
VG	Maximal transport capacity	0.06	0.31	mmol/min/ml tissue
VH	Maximal phosphorylation capacity	0.13	0.26	mmol/min/ml tissue
${\mathrm{K}}_{\mathrm{g}}^{\mathrm{G}}$	Michaelis constant for glucose transport by GLUT4	3.5	3.5	mM
${\mathrm{K}}_{2\mathrm{FDG}}^{\mathrm{G}}$	Michaelis constant for 2FDG transport by GLUT4	8	8	mM
${\mathrm{K}}_{6\mathrm{FDG}}^{\mathrm{G}}$	Michaelis constant for 6FDG transport by GLUT4	10	10	mM
${\mathrm{K}}_{\mathrm{g}}^{\mathrm{H}}$	Michaelis constant for phosphorylation of glucose	0.13	0.13	mM
${\mathrm{K}}_{2\mathrm{FDG}}^{\mathrm{H}}$	Michaelis constant for phosphorylation of 2FDG	0.17	0.17	mM
CI	Cellular influx	0.0369	0.1435	mmol/min/ml tissue
CE	Cellular efflux	0.0009	0.0115	mmol/min/ml tissue
PR	Phosphorylation rate	0.0360	0.1320	mmol/min/ml tissue