Table 5.
500 sets of parameter estimates (mean ± SD) | ||||||
---|---|---|---|---|---|---|
Basal conditions | True | Assumed | k1 (mL/mL min−1) | ISg (mM) | ICg (mM) | fIS |
True Michaelis constants | 0.040 ± 0.001 | 5.12 ± 0.04 | 0.13 ± 0.16 | 0.25 ± 0.00 | ||
3.5 | 2.8 | 0.040 ± 0.001 | 4.94 ± 0.06 | 0.15 ± 0.17 | 0.25 ± 0.00 | |
3.5 | 4.5 | 0.040 ± 0.001 | 5.25 ± 0.03 | 0.12 ± 0.16 | 0.25 ± 0.00 | |
0.13 | 0.104 | 0.040 ± 0.001 | 5.11 ± 0.04 | 0.12 ± 0.15 | 0.25 ± 0.00 | |
0.13 | 0.156 | 0.040 ± 0.001 | 5.12 ± 0.04 | 0.12 ± 0.16 | 0.25 ± 0.02 | |
10 | 8 | 0.040 ± 0.001 | 5.11 ± 0.03 | 0.01 ± 0.02 | 0.24 ± 0.00 | |
10 | 12 | 0.040 ± 0.001 | 5.15 ± 0.04 | 0.36 ± 0.16 | 0.25 ± 0.00 | |
8 | 6.4 | 0.040 ± 0.001 | 5.29 ± 0.03 | 0.37 ± 0.15 | 0.25 ± 0.00 | |
8 | 9.6 | 0.040 ± 0.001 | 4.96 ± 0.03 | 0.02 ± 0.04 | 0.24 ± 0.00 | |
0.17 | 0.136 | 0.040 ± 0.001 | 5.12 ± 0.05 | 0.12 ± 0.15 | 0.25 ± 0.00 | |
0.17 | 0.204 | 0.040 ± 0.001 | 5.12 ± 0.04 | 0.12 ± 0.15 | 0.25 ± 0.00 |