(A) Standardized adjusted hazard ratios (HRs) and 95% confidence interval (CI) for regulated on activation normal T-cell expressed and secreted (RANTES), interferon-γ-inducible protein-10 (IP-10), monocyte chemoattractant protein-1 (MCP-1), and eotaxin-1 for coronary heart disease (CHD). The PRIME Study. HRs were estimated by conditional logistic regression and expressed for a 1-SD increase in the log-transformed chemokine values in controls. Model 1 = unadjusted analysis. Model 2 = model 1 + hypertension, smoking, diabetes, body mass index (BMI), high-density lipoprotein (HDL) and total cholesterol, triglycerides. Model 3 = model 2 + high sensitivity C-reactive protein (hs-CRP) and fibrinogen. (B) Standardized adjusted HRs and 95% CI for RANTES, IP-10, MCP-1, and eotaxin-1 for ischemic stroke. The PRIME Study. HRs were estimated by conditional logistic regression and expressed for a 1-SD increase in the log-transformed chemokine values in controls. Model 1 = unadjusted analysis. Model 2 = model 1 + hypertension, smoking, diabetes, BMI, HDL and total cholesterol, triglycerides. Model 3 = model 2 + hs-CRP and fibrinogen.