TABLE 3.
Recruitment analyses (n = 24).
| Trial design characteristic (independent variable) | Range | Actual recruitment rate
|
Ratio of actual to planned recruitment rate
|
||||
|---|---|---|---|---|---|---|---|
| Parameter estimate1 | Test statistic (df) | P-value | Parameter estimate1 | Test statistic (df) | P-value | ||
| Type of intervention | Medication | −.757 | F(2,21) = 1.22 | .315 | −.305 | F(2,21) = 2.38 | .117 |
| Psychosocial | .000 | .000 | |||||
| Combination | −.905 | −.033 | |||||
| Type of therapy | Individual | .000 | F(2,21) = .63 | .544 | .000 | F(2,21) = 3.13 | .065 |
| Group | −.509 | .260 | |||||
| Combination | −.664 | −.130 | |||||
| Number of CRF pages at baseline2 | 22–131 | −.001 | t(22) = −.13 | .899 | .002 | t(22) = .94 | .355 |
| Number of treatment sessions | 1–24 | −.066 | t(22) = −2.01 | .057 | −.020 | t(22) = −3.49 | .002 |
| Duration of treatment | 1 day–24 weeks3 | −.064 | t(22) = −1.49 | .152 | −.012 | t(22) = −1.39 | .178 |
| Number of follow-up visits | 1–8 | −.129 | t(22) = −.68 | .504 | −.040 | t(22) = −1.05 | .304 |
| Duration of trial (weeks) | 4–54 | −.011 | t(22) = −.47 | .644 | −.008 | t(22) = −1.79 | .087 |
| Total number of CRF pages for trial2 | 67–917 | −.002 | t(22) = −1.57 | .131 | −.0003 | t(22) = −1.07 | .296 |
Notes:
1
Value of additional effect (for categorical variables in ANOVA) or of slope (for continuous variables in regression). For categorical variables (ANOVA), the statistical software used (SAS®) sets the parameter value at 0 for the last category, after ordering the categories alphabetically.
2
The amount of information collected on one case report form (CRF) page varies across instruments and trials.
3
In one trial, booster treatment sessions occurred up to 52 weeks post-randomization.