TABLE 3.
Trial design characteristic (independent variable) | Range | Actual recruitment rate
|
Ratio of actual to planned recruitment rate
|
||||
---|---|---|---|---|---|---|---|
Parameter estimate1 | Test statistic (df) | P-value | Parameter estimate1 | Test statistic (df) | P-value | ||
Type of intervention | Medication | −.757 | F(2,21) = 1.22 | .315 | −.305 | F(2,21) = 2.38 | .117 |
Psychosocial | .000 | .000 | |||||
Combination | −.905 | −.033 | |||||
Type of therapy | Individual | .000 | F(2,21) = .63 | .544 | .000 | F(2,21) = 3.13 | .065 |
Group | −.509 | .260 | |||||
Combination | −.664 | −.130 | |||||
Number of CRF pages at baseline2 | 22–131 | −.001 | t(22) = −.13 | .899 | .002 | t(22) = .94 | .355 |
Number of treatment sessions | 1–24 | −.066 | t(22) = −2.01 | .057 | −.020 | t(22) = −3.49 | .002 |
Duration of treatment | 1 day–24 weeks3 | −.064 | t(22) = −1.49 | .152 | −.012 | t(22) = −1.39 | .178 |
Number of follow-up visits | 1–8 | −.129 | t(22) = −.68 | .504 | −.040 | t(22) = −1.05 | .304 |
Duration of trial (weeks) | 4–54 | −.011 | t(22) = −.47 | .644 | −.008 | t(22) = −1.79 | .087 |
Total number of CRF pages for trial2 | 67–917 | −.002 | t(22) = −1.57 | .131 | −.0003 | t(22) = −1.07 | .296 |
Notes:
Value of additional effect (for categorical variables in ANOVA) or of slope (for continuous variables in regression). For categorical variables (ANOVA), the statistical software used (SAS®) sets the parameter value at 0 for the last category, after ordering the categories alphabetically.
The amount of information collected on one case report form (CRF) page varies across instruments and trials.
In one trial, booster treatment sessions occurred up to 52 weeks post-randomization.