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. Author manuscript; available in PMC: 2011 Sep 15.
Published in final edited form as: JAMA. 2010 Nov 24;304(20):2253–2262. doi: 10.1001/jama.2010.1710

Table 4. Change in Fitness, Body Composition, and Strength Variablesa.

Characteristics Mean (95% Confidence Interval)a

Control Resistance Aerobic Combination
Intention-to-Treat Analysis (n = 262)
Peak V̇O2, mL/kg per min −0.3 (−1.0 to 0.4) 0.0 (−0.5 to 0.6) 0.5 (0.01 to 1.0) 1.0 (0.5 to 1.5)g

Peak lean V̇O2, mL/kg muscle per min −0.3 (−1.4 to 0.8) −0.5 (−1.3 to 0.3) 0.7 (−0.2 to 1.5) 1.2 (0.4 to 2.0)g

Time on treadmill, minutes −0.6 (−1.4 to 0.1) 0.4 (−0.2 to 1.0)e 2.2 (1.6 to 2.7)g 2.4 (1.9 to 3.0)g

Speed/grade estimated MET −0.2 (−0.5 to 0.1) 0.2 (−0.01 to 0.3)e 0.8 (0.6 to 1.0)g 0.8 (0.6 to 1.0)g

Muscular work, N mb 89 (−48 to 226) 542 (441 to 644)d 115 (10 to 221) 273 (174 to 372)d

Muscular torque, n m/kg lean massb 0.04 (−.08 to 0.16) 0.18 (0.09 to 0.27)f −0.07 (−0.17 to 0.02) 0.15 (0.06 to 0.24)f

Body mass, kg 0.4 (−0.7 to 1.5) −0.3 (−1.1 to 0.5) −0.8 (−1.6 to 0.1) −1.5 (−2.3 to −0.7)g

Fat mass, kgc 0.1 (−0.7 to 1.0) −1.4 (−2.0 to −0.7)e −0.6 (−1.2 to −0.1) −1.7 (−2.3 to −1.1)e,f

Lean mass, kgc 0.1 (−0.5 to 0.8) 0.8 (0.4 to 1.3) −0.5 (−1.0 to 0.1)h 0.0 (−0.5 to 0.4)h

Waist circumference, cm 0.7 (−0.6 to 1.9)d −1.9 (−2.8 to −1.0) −1.5 (−2.5 to −0.6) −2.8 (−3.7 to −1.9)

Per-Protocol Analysis (n = 215)
Peak V̇O2, mL/kg per min −0.3 (−1.0 to 0.4) 0.1 (−0.4 to 0.7) 0.6 (−0.1 to 1.2) 1.1 (0.6 to 1.7)g

Peak lean V̇O2, mL/kg muscle per min −0.3 (−1.4 to 0.8) −0.4 (−1.3 to 0.5) 0.7 (−0.3 to 1.6) 1.4 (0.5 to 2.3)g

Time on treadmill, minutes −0.6 (−1.4 to 0.2) 0.5 (−0.1 to 1.1)e 2.3 (1.6 to 3.0)g 2.5 (1.8 to 3.1)g

Speed/grade estimated MET −0.2 (−0.5 to 0.1) 0.3 (−0.5 to 0.1)e 0.9 (0.6 to 1.1)g 0.8 (0.5 to 1.0)g

Muscular work, N m 89 (−54 to 231) 585 (471 to 699)d 105 (−15 to 226) 280 (169 to 392)d

Muscular torque, N m/kg lean mass 0.04 (−.08 to 0.16) 0.21 (0.11 to 0.30)e,f −0.10 (−0.20 to 0.00) 0.14 (0.04 to 0.24)f

Body mass, kg 0.4 (−0.7 to 1.5) −0.2 (−1.1 to 0.7) −0.8 (−1.8 to 0.1) −1.6 (−2.4 to −0.7)g

Fat mass, kgc 0.1 (−0.7 to 1.0) −1.3 (−1.9 to −0.6)e −0.7 (−1.4 to 0.0) −1.8 (−2.5 to −1.1)e,f

Lean mass, kgc 0.1 (−0.5 to 0.7) 0.9 (0.4 to 1.3) −0.4 (−1.0 to 0.1)h 0.0 (−0.5 to 0.5)h

Waist circumference, cm 0.7 (−0.6 to 2.0)d −2.0 (−3.1 to −1.0) −1.6 (−2.7 to −0.4) −2.7 (−3.7 to −1.7)

Abbreviations: MET, metabolic equivalent task; N m, Newton-meters; V̇O2, volume of oxygen consumed.

a

Values are expressed as fitted mean (95% CI) and all are adjusted for baseline value, age, sex, duration of diabetes and race/ethnicity with the fitness variables also adjusted for maximum heart rate during exercise testing at baseline and follow-up.

b

Peak torque was determined as the best of 5 maximal repetitions and then divided by lean mass. Total work (N m) was determined as the total work accomplished for 30 repetitions of maximal effort.

c

Due to equipment failure n = 253 for the Intention-to-Treat analysis and n = 209 for Per-Protocol analysis.

d

Significantly (P≤ .05) different from all other groups.

e

Significantly (P≤ .05) different from control group.

f

Significantly (P≤ .05) different from aerobic training group.

g

Significantly (P≤ .05) different from control group and resistance training group.

h

Significantly (P≤ .05) different from resistance training group.