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. 2011 Aug 19;6:60. doi: 10.1186/1750-1326-6-60

Figure 5.

Figure 5

Markers of CREB function and apoptosis in AD-post mortem brain. Post-mortem hippocampal samples (8 each) of AD cases and age-matched controls with equal protein content were electrophoresed, transferred, and immunoprobed with antibodies for markers of CREB function and apoptosis. The blots were reprobed for β actin. Representative images are provided. Decreases in CREB-regulated proteins that improve neuronal survival and increases in the levels of the active form of caspase-9, a marker for the intrinsic pathway of apoptosis were observed in AD-post mortem brain.