Table 1. Probable-pathogenic variants of OTOF identified in 76 patients.
Location | Nucleotide change | Codon change | Occurrence in the present work | Occurrence in control | References |
Exon 12 | c.1102G>A | p.G368R | 1/76 | 0/105 | Present work |
Exon 12 | c.1194T>A | p.D398E | 1/76 | 0/105 | [16] |
Exon 18 | c.2180A>G | p.N727S | 1/76 | 0/105 | Present work |
Intron 28 | c.3570+2T>C | Splice site | 1/76 | 0/105 | Present work |
Intron 32 | c.4023+1G>A | Splice site | 1/76 | 0/105 | Present work |
Exon 40 | C.5026C>T | p.R1676C | 1/76 | 0/105 | Present work |