Table 1. Demographic and neuropsychological data between aMCI group and healthy controls group.
| Items | Baseline | Follow up | ||||||
| aMCI group (n = 26) | controls group (n = 18) | P (MWU) | Effect size | aMCI group (n = 26) | controls group (n = 17)△ | P(MWU) | Effect size | |
| Age (years) | 71.4±4.3 | 70.3±4.7 | 0.357 | - | - | - | - | - |
| Education levels (years) | 13.8±2.8 | 15.1±3.1 | 0.084 | - | - | - | - | - |
| Gender (male: female) | 19∶7 | 10∶8 | 0.233 | - | 19∶7 | 9∶8 | 0.233 | - |
| Clinical dementia rating (CDR) | 0.5 | 0 | - | - | 0.5 | 0 | - | - |
| Mini mental state exam (MMSE) | 27.2±1.5 | 28.3±1.3 | 0.026* | 0.76 | 27.2±2.1 | 28.6±1.8 | 0.01* | 0.69 |
| Auditory verbal memory test- delayed recall | 2.8±1.2 | 8.1±1.9 | 0.000* | 3.42 | 4.2±2.2 | 8.6±2.7 | 0.000* | 1.79 |
| Rey-Osterrieth complex figure test | 32.9±4.7 | 34.7±1.4 | 0.471 | 0.47 | 34.0±2.9 | 35.0±0.8 | 0.715 | 0.42 |
| Rey-Osterrieth complex figure test-delayed recall | 12.0±7.4 | 17.3±6.8 | 0.017* | 0.73 | 12.9±7.6 | 20.9±7.4 | 0.002* | 1.04 |
| Trail making test-A (seconds)Trail making test-B (seconds) | 88.7±36.2182.3±70.4 | 70.0±28.7139.3±39.2 | 0.049*0.046* | 0.550.71 | 95.1±44.3175.6±82.8 | 75.7±26.0138.8±55.1 | 0.0960.099 | 0.500.49 |
| Symbol digit modalities test | 27.7±10.4 | 34.3±8.7 | 0.043* | 0.66 | 29.0±11.4 | 33.2±13.0 | 0.164 | 0.34 |
| Clock drawing test | 8.5±1.6 | 8.9±1.2 | 0.231 | 0.27 | 8.8±2.0 | 9.1±0.9 | 0.689 | 0.17 |
| Digit span test | 12.2±2.0 | 13.2±1.8 | 0.09 | 0.51 | 12.7±2.0 | 13.6±2.5 | 0.303 | 0.40 |
Values are mean ± (SD); MWU: Mann-Whitney U-test, which was used here due to the neuropsychological data were not normally distributed;
*indicates had statistical difference between groups, P<0.05. Δ: One subject of follow-up neuropsychological data in healthy controls was absent. Effect size for distinguishing groups using Hedges g scores, accounting for sample sizes.