Table 5. Baseline Characteristics of patients with NS5A aa 2224–2242 variations none or 1≤.
Characteristic | Variation 1≤ (n = 33) | No variation (n = 27) | P value |
Gender (Male/Female) | 17/16 | 18/9 | NS† |
Age (yrs) | 57 (29–72)* | 57 (22–80) | NS‡ |
ALT (IU/l) | 72 (19–380) | 47 (17–390) | NS‡ |
Platelet (×104/mm3) | 19.3 (7.1–31.8) | 17.5 (10.4–36.7) | NS‡ |
Fibrosis score (0–2/≥3)§ | 26/5 | 19/3 | NS† |
HCV RNA (KIU/ml) | 1600 (100–16000) | 2450 (140–13000) | NS‡ |
IFN dose (≥80%/60–80%) | 26/7 | 23/4 | NS† |
Ribavirin dose (≥80%/60–80%) | 24/9 | 19/8 | NS† |
RVR rate (%) | 53.1 | 29.6 | NS† |
EVR rate (%) | 96.9 | 81.5 | NS† |
SVR rate (%) | 90.9 | 51.9 | 0.001† |
Replapse rate (%) | 40.7 | 9.1 | 0.006† |
: 1≤ : n = 31, 0 : n = 22.
: median (range).
: Fisher's exact probability test.
: Mann-Whitney's U test.