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. 2011 Sep 15;6(9):e24514. doi: 10.1371/journal.pone.0024514

Table 5. Baseline Characteristics of patients with NS5A aa 2224–2242 variations none or 1≤.

Characteristic Variation 1≤ (n = 33) No variation (n = 27) P value
Gender (Male/Female) 17/16 18/9 NS
Age (yrs) 57 (29–72)* 57 (22–80) NS
ALT (IU/l) 72 (19–380) 47 (17–390) NS
Platelet (×104/mm3) 19.3 (7.1–31.8) 17.5 (10.4–36.7) NS
Fibrosis score (0–2/≥3)§ 26/5 19/3 NS
HCV RNA (KIU/ml) 1600 (100–16000) 2450 (140–13000) NS
IFN dose (≥80%/60–80%) 26/7 23/4 NS
Ribavirin dose (≥80%/60–80%) 24/9 19/8 NS
RVR rate (%) 53.1 29.6 NS
EVR rate (%) 96.9 81.5 NS
SVR rate (%) 90.9 51.9 0.001
Replapse rate (%) 40.7 9.1 0.006
§

: 1≤ : n = 31, 0 : n = 22.

*

: median (range).

: Fisher's exact probability test.

: Mann-Whitney's U test.