Table 2. Ratio of ORmale:ORfemale for 12 risk loci identified by genome-wide association studies of female breast cancer.
SNP | Chromosome | ORmale:ORfemale (95% CI) | χ2 | P-valuea |
rs11249433 | 1p11.2 | 0.95 (0.80–1.11) | 0.425 | 0.50 |
rs13387042 | 2q35 | 1.19 (1.01–1.39) | 4.538 | 0.03 |
rs4973768 | 3p24.1 | 1.07 (0.91–1.25) | 0.681 | 0.41 |
rs10941679 | 5p12 | 1.03 (0.86–1.22) | 0.087 | 0.77 |
rs16886165 | 5q11.2 | 0.81 (0.65–1.02) | 3.116 | 0.08 |
rs9383938 | 6q25.1 | 1.22 (0.95–1.58) | 2.400 | 0.12 |
rs13281615 | 8q24.21 | 1.02 (0.87–1.20) | 0.036 | 0.85 |
rs865686 | 9q31.2 | 0.95 (0.80–1.13) | 0.293 | 0.59 |
rs2981579 | 10q26.13 | 0.96 (0.82–1.12) | 0.315 | 0.57 |
rs3817198 | 11p15.5 | 0.87 (0.74–1.03) | 2.646 | 0.10 |
rs3803662 | 16q12.1 | 1.19 (1.01–1.42) | 4.118 | 0.04 |
rs6504950 | 17q22 | 0.84 (0.71–0.99) | 4.086 | 0.04 |
All SNPs combined | 22.769 | 0.03 |
P value for null hypothesis of no difference between ORmale and ORfemale for each SNP individually and for all SNPs combined (in bold).