Table 1. List, characteristics, and Allergome reference code for the three panallergen groups, ranked by prevalence of IgE reactivity among and within groups.
Panallergens | IgE Reactive Patients | ||||||
Allergen | Common name | Allergome Code | Molecule Sequence Identity° | N. | % | N. | % |
Mer a 1 | Profilin | 476 | 100 | 1,521 | 48.8 | 1181 | 77.6 |
Hev b 8 | 397 | 81 | 1019 | 67.0 | |||
Bet v 2 | 127 | 84 | 986 | 64.8 | |||
Ole e 2 * | 490 | 85 | 977 | 64.2 | |||
Hel a 2 | 377 | 75 | 889 | 58.4 | |||
Pho d 2 | 571 | 80 | 876 | 57.6 | |||
Cyn d 12 | 279 | 76 | 857 | 56.3 | |||
Par j 3 | 510 | 78 | 688 | 45.2 | |||
Phl p 12 | 553 | 82 | 551 | 36.2 | |||
Bet v 1 | PR-10 | 89 | 100 | 1,420 | 45.6 | 1314 | 92.5 |
Cor a 1 | 232 | 83 | 960 | 67.6 | |||
Aln g 1 | 7 | 81 | 741 | 52.2 | |||
Mal d 1 | 464 | 65 | 696 | 49.0 | |||
Api g 1 | 40 | 41 | 163 | 11.5 | |||
Dau c 1 | 287 | 39 | 59 | 4.2 | |||
Der p 10 | Tropomyosin | 311 | 100 | 632 | 20.3 | 430 | 68.0 |
Pen i 1 * | 527 | ≈80# | 326 | 51.6 | |||
Pen m 1 * | 872 | 80 | 313 | 49.5 | |||
Ani s 3 | 37 | 73 | 313 | 49.5 | |||
Hel as 1 | 378 | 64 | 309 | 48.9 | |||
Per a 7 | 542 | 79 | 272 | 43.0 |
Natural purified molecules, all others are E.coli-produced recombinants. Biochemical, immunological and clinical details on each allergen are available at www.allergome.org.
°Generated using AllergomeAligner (www.allergome.org) assuming the first ranked IgE reactive allergen as reference sequence ( = 100%).
Complete Pen i 1 sequence is not available. From peptide fragment matching and IgE reactivity it is assumed to be close to Pen m 1.