Skip to main content
. Author manuscript; available in PMC: 2012 Sep 15.
Published in final edited form as: Cancer Res. 2011 Jul 27;71(18):6030–6039. doi: 10.1158/0008-5472.CAN-10-2719

Figure 2. VEGF increases Dll4 expression in endothelial cells.

Figure 2

(a) RT-PCR analysis of Notch ligands and receptors in non-transformed ovarian epithelial (HIO180), ovarian cancer (HeyA8, SKOV3ip1, OVCAR3, A2774, A2780, IGROV), endothelial (HUVEC, MOEC), and pericyte-like (10T1/2) cells. (b) Western blot analysis of Dll4 expression in the tissues obtained from SKOV3ip1 and A2780 ovarian cancer models. (c, d) RT-PCR and real time RT-PCR analysis of Dll4 expression in MOECs after exposure to VEGF or basic fibroblast growth factor (bFGF) for 48 hours under hypoxic (1% O2) conditions.