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. 2011 Sep;164(2):278–293. doi: 10.1111/j.1476-5381.2011.01345.x

Figure 5.

Figure 5

Post-treatment with AT-RvD1) (100 or 300 ng/i.p., 3 days after) (A,B), with the resolvins D series precursor 17(R)HDoHE (300 ng/i.p., 3 days after, for 5 days) (C,D) or with AT-RvD1 (100 ng/i.p., 3 days after, for 4 days) (E,F) partially inhibited mechanical hyperalgesia (ipsilateral hind paw) induced by adjuvant-induced arthritis (AIA). Data are presented as the mean ± SEM of four to six animals per group. *P < 0.05 and #P < 0.05 are significantly different from the vehicle and complete Freund's Adjuvant (CFA) groups respectively. The arrow (↓) above X-axis represent the treatment with AT-RvD1 or 17(R)HDoHE.; d3, day 3 after AIA induction.