Figure 3.

Effects of D₁ and D₂ antagonism on DNQX-induced eating and defensive fearful behaviors. Fos plume maps (n = 23) in sagittal plane of the generation in medial shell of eating (A), defensive treading (B), and fearful vocalizations and escape attempts (C) by DNQX (left), DNQX plus SCH23390 (D₁ antagonist, middle), and DNQX plus raclopride (D₂ antagonist, right). The D₁ antagonist prevented DNQX from generating either eating or fear, whereas the D₂ antagonist left DNQX-induced eating intact but prevented DNQX-induced generation of fear. Histogram bars below the maps show behavior as a percentage of vehicle (eating, A; treading, B) or percentage of subjects (vocalizations and escape attempts, C) for each behavior at rostrocaudal level as marked along the medial shell (error bars indicate SEM).