Table 3.
Effects of Oral Administration of M. charantia on Diabetes Mellitus
Experimental Models | Parts of Plant used | Effects | References |
---|---|---|---|
Normal and diabetic rats | Whole plant | Beneficial | Leatherdale et al. [26] |
Jeevathayaparan et al. [27] | |||
Chandrasekar et al. [28] | |||
Diabetic rats | Ethanol extract of whole plant | Beneficial | Chandrasekar et al. [29] |
Normal and diabetic rats | Fruit juice and various extracts | Beneficial | Ali et al. [30, 31] |
Human (NIDDM) | Fruit juice/leaves | Beneficial | William and Pickup [6]; Ahmad et al. [45] |
Human (NIDDM) | Fruit juice | No effect | Patel et al. [12], Day and Bailey [8] |
Human (NIDDM) | Fruit powder | Beneficial | Akhtar et al. [32], Ahmed et al. [33] |
Normal rabbits | Fruit juice | No effect | Kulkarni et al. [23] |
Diabetic rabbits | Fruit juice | Beneficial | Akhtar et al. [32] |
Normal and diabetic rats | Fruit juice | No effect | Karunanayake et al. [24] Platel and Srinivasan [16, 17] |
Normal and diabetic rats | Fruit juice | Beneficial | Srivastavaet et al. [49]: Karunanayake et al. [24] |
Normal and diabetic rat | Fruit juice | Beneficial | Sharma et al. [37]; Day et al. [19] |
Normal and diabetic rats | Seed | Beneficial | Kedar and Chakrabarti [35] |
Normal and diabetic rats | Fruit juice | Beneficial | Sharma et al. [34] |