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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: J Neurochem. 2011 Aug 22;119(1):189–201. doi: 10.1111/j.1471-4159.2011.07389.x

Table 3. MAbs 3C6 and 4B5 binding to plate-immobilized and solution-phase amyloidogenic conformers.

NB, no binding, and ND, not determined

Aβ Conformer 3C6 4B5
Plate Solution Plate Solution
(Aβ1-40S26C)2 monomers X X X X
(Aβ1-40S26C)2 dimers √ X √ X
Reduced (Aβ1-40S26C)2 dimers X ND X ND
(Aβ1-40S26C)2 protofibrils √ √ √ √
WT Aβ1-40 monomers X X X X
Aβ1-40 fibrils √ √ √ √
IAPP fibrils NB ND NB ND
Jto fibrils NB ND NB ND