Fig. 1.

Deactivation and desensitization characteristics of transient receptor potential ankyrin 1 (TRPA1). A: N-methyl maleimide (NMM)- and allyl isothiocyanate (AITC)-induced currents are readily reversible by agonist washout. B: at higher concentrations, continued presence of NMM and AITC caused complete desensitization of the responses. C: deactivation phases can be well-fitted with two exponential functions. D: the desensitization phases can be well-fitted with a single exponential function.