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Dose-response and current-voltage relationship curves of TRPA1- induced currents. A: cumulative dose response to increasing concentrations of AITC. B: dose-response curves of NMM and AITC. C: a ramp current-voltage relationship. D: single-channel current-voltage relationship. Note that the single-channel open probability (Po) is lower at −80 mV as compared with +80 mV.
