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. 2011 Aug 30;108(37):15432–15437. doi: 10.1073/pnas.1112667108

Fig. 2.

Fig. 2.

TS2-neo mice exhibited no sign of increased anxiety in light/dark box and elevated zero maze. (A) Light/dark box: mice were exposed to an activity chamber with dark and bright sides for 10 min. (B) Percentage of time spent in dark side. No significant difference between TS2-neo and WT mice for time course (P > 0.8 for genotype effect, ANOVA) (Left) or cumulative time (P > 0.8, Student's t test) (Right). n (WT) = 13, n (TS2-neo) = 12. (C) Elevated zero maze: mice were exposed to elevated, annular platform with two closed and two open quadrants for 8 min. n (WT) = 9, n (TS2-neo) = 13. (D) No significant difference between TS2-neo and WT littermates for time course (P > 0.6 for genotype effect, ANOVA) (Left) and cumulative time spent in closed quadrants (P > 0.2, Mann–Whitney u test) (Right).