Table 1.
Demographic and clinical characteristics of patients with PBD and HC
| Variables | PBD (n=17)
|
HC (n=13)
|
Analyses
|
||
|---|---|---|---|---|---|
| Mean (SD) | N (%) | Mean (SD) | N (%) | F (p value) | |
| Age (years) | 14.29 (2.05) | 14.38 (3.57) | 0.008 (.93) | ||
| WASI-FSIQa | 97 (8.12) | 104 (10.10) | 3.98 (.06) | ||
| Socioeconomic statusb | 2.34 (.63) | 1.92 (1.12) | 1.63 (.21) | ||
| YMRS (group by time interaction) | 6.98 (.01) | ||||
| YMRS at baseline | 14.59 (7.00) | 1.08 (1.6) | 46.20 (.000001) | ||
| YMRS at follow-up | 6.47 (7.80)* | 0.77 (1.36) | 6.73 (.02) | ||
| CDRS (group by time interaction) | 20.48 (.0001) | ||||
| CDRS-R at baseline | 50.47 (12.95)* | 19.0 (1.29) | 75.60 (.000001) | ||
| CDRS-R at follow-up | 29.71 (15.41) | 18.8 (1.11) | 6.39 (.02) | ||
| Sex | (.45) | ||||
| Male | 5 (29%) | 6 (46%) | |||
| Female | 12 (71%) | 7 (54%) | |||
| Race | (.71) | ||||
| Caucasian | 12 (71%) | 8 (62%) | |||
| Other | 5 (29%) | 5 (38%) | |||
| Handedness | (1.00) | ||||
| Right-handed | 16 (94%) | 13 (100%) | |||
| Left-handed | 1 (6%) | 0 (0%) | |||
WASI IQ Wechsler Abbreviated Scale of Intelligence Intelligent Quotient, PBD pediatric bipolar disorder, HC healthy control, YMRS young mania rating scale, CDRS-R child depression rating scale-revised
*
p<. 000001, significant score difference at follow-up relative to baseline
a
Wechsler Abbreviated Scale of Intelligence Intelligent Quotient (Matrix Reasoning and Vocabulary Subtests)
b
Mean revised Hollingshead socioeconomic status