Table 3.
Between-group comparisons for angry or happy face condition at baseline
| Group difference | Talairach coordinates for peak values | Area | BA | Volume (mm3) | t value for peak values |
|---|---|---|---|---|---|
| Angry vs neutral | |||||
| HC>PBD | −46, 20, 8 | L inferior frontal gyrus | BA 45 | 1,134 | 4.57 |
| HC>PBD | −46, 33, 0 | L inferior frontal gyrus | BA 47 | 351 | 2.89 |
| HC>PBD | 15, 8, 11 | R dorsal caudate | 432 | 3.89 | |
| Happy vs neutral | |||||
| PBD>HC | 25, −1, −13 | R amygdala | 351 | 2.53 | |
| PBD>HC | 53, 35, 9 | R inferior frontal gyrus | BA 45/46 | 486 | 3.84 |
| PBD>HC | −34, 23, −7 | L inferior frontal gyrus | BA 47 | 1,539 | 2.85 |
| PBD>HC | 59, 8, 20 | R middle frontal gyrus | BA 44, 9 | 1,458 | 3.46 |
| PBD>HC | 41, 47, 11 | R middle frontal gyrus | BA 10, 46 | 1,512 | 3.89 |
| PBD>HC | −13, 59, 20 | L medial frontal gyrus | BA 10 | 837 | 4.82 |
| PBD>HC | 53, −58, −7 | R middle temporal gyrus | BA 22 | 513 | 3.16 |
Talairach coordinates and t values for clusters for which there is a significant three-way interaction (corrected p<0.020 with cluster contiguity threshold) in the whole-brain ANOVA for the angry or happy face condition. The table also lists the significant group differences obtained from post hoc decomposition of the significant interaction
HC healthy control group, PBD pediatric bipolar disorder group, BA Brodmann’s area, L left, R right