Cellular production of adenosine. CD39, nucleoside triphosphate diphosphohydrolase; CD73, ecto-5′-nucleotidase; 5NT, endo-5′-nucleotidase; AK, adenosine kinase; SAH, S-adenosyl homocysteine; cylinder, exocytosis exportation; circle, equilibrative membrane transporter. SAH hydrolase reversibly catalyses the degradation of SAH to adenosine and homocysteine. [Modified from Fredholm et al. (93).]