Fig. 2.

Isometric force. Maximal isometric force production was measured longitudinally in vivo in the plantar flexor muscles before experimental intervention (time 0), after 14 days of HS, and after 14 days of HS followed by 14 days of R. Animals received either HMB, or the vehicle (water) daily, for 7 days before time 0 and throughout the experimental period. An ANOVA followed by Bonferroni post hoc analyses was used to evaluate the differences between the group means. †P < 0.05, vehicle vs. HMB; *force/body weight was significantly lower (P < 0.05) compare to points before HS for the same treatment; **force/body weight was significantly lower (P < 0.05) in vehicle and HMB-treated groups after both HS and R compared with CC-Veh or CC-HMB groups.