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. 2011 Jun 16;111(3):834–843. doi: 10.1152/japplphysiol.00031.2011

Fig. 5.

Fig. 5.

Aging MGsKO mice contained pure slow fibers in soleus muscle. A: SDS-PAGE, glycerol-SDS gel, and Western blots showed that soleus muscles of 18- to 24-mo-old MGsKO mice expressed solely MHC I, slow TnI, and slow TnT. Aging also produced switches to more slow isoforms of myofilament proteins in control soleus muscle compared with that in the 3-mo-old control group (Fig. 1A). B: immunohistochemistry using MAb FA2 against MHC I showed 100% type I fibers in the soleus muscle of aging MGsKO mice.