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. 2011 Oct 1;34(10):1309–1316. doi: 10.5665/SLEEP.1268

Table S1.

Complete results for single marker association analyses of sleep duration as well as short and long sleep in females (N = 1626) and males (N = 1521) from the population-based Health 2000 and FINRISK study 2007 samples.

Chr Gene SNPs BP A1/A2 Females
 Males
Sleep durationa
 Short sleep vs.midrange sleepb
 Long sleep vs.midrange sleepb
 Sleep durationa
 Short sleep vs.midrange sleepb
 Long sleep vs.midrange sleepb
MAF β (95% CI) P MAF OR (95% CI) P MAF OR (95% CI) P MAF β (95% CI) P MAF OR (95% CI) P MAF OR (95% CI) P
1 DISC1 rs3738401 228137030 G/A 0.28 -0.051 (-0.12-0.025) 0.190 0.31 1.11 (0.88-1.40) 0.353 0.26 0.90 (0.71-1.13) 0.374 0.29 0.005 (-0.07-0.08) 0.891 0.29 1.02 (0.82-1.27) 0.819 0.30 1.05 (0.79-1.39) 0.705
2 NPAS2 rs12712083 100875331 A/G 0.43 0.005 (-0.06-0.076) 0.873 0.43 0.96 (0.77-1.2) 0.740 0.42 0.92 (0.75-1.14) 0.479 0.43 0.052 (-0.02-0.12) 0.154 0.42 0.94 (0.77-1.15) 0.595 0.43 1.05 (0.81-1.37) 0.689
9 NFIL3 rs1619450 93208976 T/C 0.14 -0.008 (-0.122-0.105) 0.887 0.15 1.18 (0.83-1.67) 0.353 0.16 1.3 (0.94-1.78) 0.108 0.13 -0.021 (-0.13-0.09) 0.721 0.17 1.01 (0.73-1.40) 0.909 0.12 1.11 (0.74-1.65) 0.627
11 ARNTL rs6486121 13312346 C/T 0.10 -0.016 (-0.087-0.054) 0.648 0.11 1.05 (0.84-1.31) 0.630 0.12 1.12 (0.91-1.38) 0.288 0.10 -0.035 (-0.10-0.03) 0.330 0.10 1.01 (0.83-1.24) 0.855 0.11 0.95 (0.73-1.23) 0.708
11 ARNTL rs3816358 13348048 C/A 0.49 0.013 (-0.088-0.116) 0.789 0.48 0.84 (0.60-1.17) 0.325 0.47 0.99 (0.73-1.35) 0.996 0.49 0.042 (-0.05-0.14) 0.418 0.49 0.95 (0.71-1.27) 0.748 0.49 1.05 (0.73-1.52) 0.768
11 ARNTL rs969485 13359619 A/G 0.14 -0.053 (-0.137-0.030) 0.204 0.13 1.13 (0.88-1.46) 0.325 0.13 0.96 (0.75-1.24) 0.804 0.14 0.0005 (-0.08-0.08) 0.991 0.13 0.89 (0.70-1.14) 0.374 0.14 1.02 (0.75-1.39) 0.895
11 BDNF rs6265 27636492 C/T 0.22 0.036 (-0.061-0.134) 0.461 0.24 1.05 (0.77-1.42) 0.742 0.21 1.05 (0.79-1.40) 0.696 0.22 -0.043 (-0.14-0.05) 0.382 0.20 1.2 (0.92-1.56) 0.176 0.22 1.04 (0.72-1.49) 0.822
11 BDNF rs1491850 27706301 T/C 0.15 0.067 (-0.003-0.139) 0.060 0.15 0.87 (0.69-1.09) 0.232 0.15 1.03 (0.84-1.28) 0.715 0.15 -0.038 (-0.10-0.03) 0.286 0.17 1.18 (0.97-1.45) 0.090 0.14 1.08 (0.83-1.40) 0.549
12 ARNTL2 rs4964060 27424634 G/A 0.41 -0.006 (-0.078-0.065) 0.862 0.38 1.03 (0.82-1.29) 0.758 0.42 0.90 (0.73-1.12) 0.381 0.43 0.019 (-0.05-0.09) 0.599 0.47 1.03 (0.84-1.26) 0.732 0.44 0.88 (0.67-1.14) 0.348
12 ARNTL2 rs7304939 27435612 C/T 0.41 0.033 (-0.088-0.155) 0.586 0.41 0.83 (0.55-1.24) 0.395 0.39 0.87 (0.60-1.25) 0.461 0.43 -0.066 (-0.18-0.05) 0.276 0.44 1.16 (0.84-1.60) 0.337 0.39 0.73 (0.44-1.20) 0.228
12 ARNTL2 rs1037921 27444833 A/G 0.09 0.006 (-0.127-0.140) 0.921 0.07 0.82 (0.52-1.28) 0.394 0.08 0.88 (0.59-1.33) 0.563 0.09 -0.097 (-0.23-0.03) 0.155 0.11 1.21 (0.85-1.71) 0.289 0.07 0.67 (0.38-1.18) 0.163
12 ARNTL2 rs2289709 27464900 C/T 0.07 0.006 (-0.101-0.115) 0.898 0.06 1.03 (0.73-1.44) 0.851 0.06 0.94 (0.68-1.31) 0.739 0.07 -0.029 (-0.14-0.08) 0.604 0.09 1.01 (0.74-1.37) 0.941 0.05 0.73 (0.46-1.15) 0.179
12 TIMELESS/ rs2291738 55101548 G/A 0.11 0.025 (-0.046-0.097) 0.491 0.11 0.81 (0.65-1.02) 0.081 0.10 0.97 (0.78-1.21) 0.844 0.11 -0.035 (-0.10-0.03) 0.339 0.11 1.22 (1.00-1.50) 0.048 0.08 1.05 (0.80-1.36) 0.706
12 TIMELESS rs1082214 55132757 C/T 0.44 -0.037 (-0.164-0.089) 0.560 0.40 1.24 (0.86-1.78) 0.242 0.44 1.05 (0.72-1.53) 0.775 0.48 0.082 (-0.05-0.21) 0.238 0.47 1.23 (0.85-1.78) 0.266 0.48 1.61 (1.04-2.50) 0.026
12 TPH2 rs12229394 70679181 G/A 0.07 -0.002 (-0.077-0.073) 0.956 0.09 1.04 (0.83-1.32) 0.681 0.07 0.92 (0.73-1.16) 0.521 0.07 0.015 (-0.06-0.09) 0.697 0.08 1.28 (1.03-1.59) 0.024 0.10 1.33 (1.00-1.76) 0.041
15 RORA rs4774370 58680723 T/C 0.30 0.056 (-0.032-0.145) 0.211 0.31 0.72 (0.53-0.97) 0.037 0.29 1.06 (0.82-1.38) 0.616 0.30 0.060 (-0.02-0.15) 0.184 0.34 0.86 (0.66-1.11) 0.257 0.35 1.07 (0.78-1.47) 0.653
15 RORA rs8027829 58961163 C/T 0.20 -0.015 (-0.090-0.059) 0.687 0.15 0.96 (0.76-1.21) 0.774 0.21 0.99 (0.79-1.24) 0.975 0.19 0.005 (-0.06-0.07) 0.877 0.17 0.90 (0.73-1.11) 0.332 0.21 0.99 (0.75-1.30) 0.952
15 RORA rs1568717 59149739 G/T 0.35 -0.051 (-0.135-0.031) 0.233 0.33 1.02 (0.78-1.32) 0.883 0.35 0.82 (0.63-1.07) 0.147 0.35 0.069 (-0.01-0.15) 0.115 0.32 0.89 (0.69-1.15) 0.397 0.34 1.18 (0.87-1.60) 0.281
15 RORA rs4774388 59254290 A/G 0.23 0.005 (-0.09-0.104) 0.905 0.24 1.12 (0.83-1.50) 0.438 0.20 1.13 (0.84-1.50) 0.403 0.21 -0.081 (-0.18-0.02) 0.125 0.19 1.42 (1.08-1.86) 0.010 0.24 0.94 (0.63-1.38) 0.760
17 SLC6A4 rs4251417 25575984 G/A 0.07 0.153 (0.017-0.288) 0.027 0.05 0.74 (0.46-1.19) 0.214 0.09 1.33 (0.92-1.92) 0.114 0.08 0.053 (-0.07-0.18) 0.422 0.07 0.96 (0.66-1.39) 0.824 0.09 1.27 (0.81-1.97) 0.281
17 CRHR1 rs173365 41256855 G/A 0.32 0.008 (-0.068-0.085) 0.831 0.32 0.98 (0.77-1.25) 0.903 0.32 0.97 (0.77-1.23) 0.861 0.29 -0.014 (-0.09-0.06) 0.722 0.31 1.10 (0.88-1.37) 0.388 0.30 1.10 (0.83-1.47) 0.492
X GRIA3 rs687577 122304639 C/A 0.11 0.270 (0.160-0.381) 0.00001* 0.08 0.84 (0.57-1.23) 0.382 0.18 1.89 (1.42-2.52) 0.00001** 0.11 0.0003 (-0.16-0.16) 0.995 0.08 0.68 (0.41-1.12) 0.129 0.07 0.62 (0.31-1.22) 0.186
X GRIA3 rs526716 122374650 G/A 0.16 -0.008 (-0.103-0.086) 0.860 0.18 1.20 (0.91-1.60) 0.181 0.18 1.19 (0.91-1.57) 0.187 0.17 -0.017 (-0.15-0.11) 0.794 0.17 1.06 (0.73-1.54) 0.750 0.17 0.97 (0.59-1.59) 0.985

Chr, chromosome; BP, base pair, reported by NCBI dbSNP database build 125 to 130; A1/A2, Major allele / Minor allele; MAF, Minor allele frequency; β, Regression coefficient; OR, Odds ratio; 95% CI, Lower and upper bound confidence interval for β or odds ratio.

a

Linear regression analysis with age and presence of metabolic disorder as covariates;

b

Logestic regression analysis with age and presence of metabolic disorder as covariates; Gene and SNPs with P-values < 0.05 as well as the corresponding MAF, β/OR -values are bolded.

*

Permutation-based corrected empirical P = 0.00001, Bonferoni P = 0.000038, P-values adjusted to the number of models (3 models in both genders, altogether 6 models) (Bonferoni corrected P = 0.0052) for association with sleep duration in females.

**

Permutation-based corrected empirical P = 0.0003, Bonferoni P = 0.00028, P-values adjusted to the number of models (3 models in both genders, altogether 6 models) (Bonferoni corrected P = 0.039) for association with long sleep in females.