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. 2011 Aug 3;12:36. doi: 10.1186/1471-2369-12-36

Table 4.

Adherence to allopurinol dosing guidelines

Hande et al. Creatinine Clearance Hande et al. Criteria Maintenance Dose of Allopurinol Study Sample eGFR Study Sample Initial Daily Dose of Allopurinol mg
0 100 mg every 3 days 0-9 n 22
mean 240.91
dose ≤ Hande maintenance dose (%) 0

10 100 mg every 2 days 10-19 n 60
mean 233.14
dose ≤ Hande maintenance dose (%) 1.67

20 100 mg daily 20-39 n 114
mean 208.95
dose ≤ Hande maintenance dose (%) 34.21

40 150 mg daily 40-59 n 245
mean 236.35
dose ≤ Hande maintenance dose (%) 29.8

60 200 mg daily 60-79 n 471
mean 244.46
dose ≤ Hande maintenance dose (%) 35.46

80 250 mg daily 80-99 n 892
mean 249.58
dose ≤ Hande maintenance dose (%) 32.96

100 300 mg daily 100-119 n 909
mean 247.34
dose ≤ Hande maintenance dose (%) 95.93

120 350 mg daily 120-139 n 389
mean 253.09
dose ≤ Hande maintenance dose (%) 94.86

140 400 mg daily 140+ n 20
mean 250
dose ≤ Hande maintenance dose (%) 95