Table 1.
Demographic and clinical characteristics among the infarct volume quartile groups
| Quartile of DWI lesion volumes, ml | P | ||||
|---|---|---|---|---|---|
| Q1 (< 3.1) n = 58 |
Q2 (3.1-11.8) n = 58 |
Q3 (11.9-44.2) n = 58 |
Q4 (> 44.2) n = 57 |
(Q4 vs. others) | |
| NISS score on admission | 4.0 ± 3.9 | 8.1 ± 6.1 | 10.8 ± 6.5 | 15.1 ± 6.8 | < 0.001 |
| Vascular risk factors | |||||
| Age | 69.0 ± 10.9 | 70.0 ± 11.1 | 72.5 ± 10.4 | 69.5 ± 11.7 | 0.547 |
| Male gender | 24(41.4%) | 26(44.8%) | 32(55.2%) | 36(63.2%) | 0.036 |
| Hypertension | 41(70.7%) | 41(70.7%) | 42(72.4%) | 36(63.2%) | 0.250 |
| Diabetes | 10(17.2%) | 13(22.4%) | 7(12.1%) | 14(24.6%) | 0.222 |
| Previous TIA/stroke | 18(31.0%) | 15(25.9%) | 13(22.4%) | 13(22.8%) | 0.585 |
| CHADS2*score | 0.871 | ||||
| 0-1 | 28(48.3.%) | 24(41.4%) | 25(43.1%) | 25(43.9%) | |
| 2-3 | 22(37.9%) | 27(6.6%) | 28(48.3%) | 24(42.1%) | |
| 4-5 | 8(13.8%) | 7(12.1%) | 5(8.6%) | 8(14.0%) | |
| Dysrhythmia | |||||
| Paroxysmal atrial fibrillation | 22(37.9%) | 22(37.9%) | 20(34.5%) | 18(31.6%) | 0.476 |
| Concomitant valvular heart disease | 5(8.8%) | 9(15.5%) | 5(8.6%) | 5(8.9%) | 0.663 |
| Heart rate (/min) | 78.1 ± 19.2 | 82.9 ± 21.6 | 85.1 ± 21.4 | 84.2 ± 23.2 | 0.480 |
| Medications prior to onset | |||||
| Antiplatelet agents user | 26(45.6%) | 20(34.5%) | 26(47.3%) | 19(33.3%) | 0.229 |
| Warfarin user | 7(12.1%) | 9(15.5%) | 4(6.9%) | 8(14.0%) | 0.610 |
| Laboratory findings | |||||
| D-dimer, mg/dL | 1.51 ± 2.85 | 2.01 ± 3.31 | 3.45 ± 12.87 | 2.06 ± 3.35 | 0.035 |
| Fibrinogen, mg/dL | 320.0 ± 83.9 | 303.0 ± 79.2 | 335.5 ± 81.9 | 346.6 ± 100.2 | 0.122 |
| C-reactive protein, mg/dL | 1.13 ± 2.95 | 0.69 ± 1.78 | 0.95 ± 2.04 | 0.80 ± 1.31 | 0.068 |
| Prothrombin Time, INR | 1.07 ± 0.11 | 1.10 ± 0.12 | 1.06 ± 0.11 | 1.06 ± 0.10 | 0.373 |
| Transthoracic echocardiogram finding | |||||
| Left ventricular ejection fraction, % | 62.1 ± 9.8 | 59.7 ± 12.4 | 60.2 ± 8.5 | 56.1 ± 15.4 | 0.020 |
| Left atrium size, ml | 48.0 ± 8.8 | 46.5 ± 9.4 | 47.8 ± 8.6 | 46.5 ± 7.2 | 0.660 |
| E/e' ratio | 13.20 ± 6.25 | 16.76 ± 9.85 | 13.84 ± 8.06 | 14.52 ± 9.00 | 0.839 |
| DT, ms | 230.5 ± 153.6 | 248.3 ± 154.5 | 207.3 ± 115.8 | 216.1 ± 114.2 | 0.925 |
*In CHADS2, S indicates prior stroke or transient ischemic attack