Table 3. Influence of high fat diet on plasma glucose and triglyceride concentrations in wild-type and mdr1ab-/- mice at 25 weeks of age.
Wild-type | Mdr1ab-/- | ||
Glucose (mmol/L) | Standard diet | 18.3±1.7 | 16.1±1.3 |
HFD | 26.9±1.7 * | 34.3±1.3 a ** | |
Triglyceride (mmol/L) | Standard diet | 0.80±0.07 | 0.92±0.04 |
HFD | 0.70±0.03 | 0.99±0.05 a |
Mice were fed from weaning to 25 weeks of age whether with a standard chow diet or a high fat diet (HFD). Glucose and triglycerides were analysed in plasma samples from wild-type and mdr1ab-/- mice. Results are expressed as means ± s.e.m. of 3 to 5 animals.
p<0.05 when compared with wild-type.
*p<0.05;
**p<0.05, when compared with standard diet.