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. 2011 Sep 16;6(9):e23893. doi: 10.1371/journal.pone.0023893

Figure 5. αPS1 function is specifically required in CVM cells to mediate their migration.

Figure 5

The ability of different UAS-αPS1 transgenes to rescue the CVM migration defects of Stg 13 αPS1 mutant embryos was assessed by co-expressing UAS-CD2 and the different transgenes using the G447.2-GAL4 and staining with anti-CD2 antibody. (A) Wild type embryo. (B) αPS1 mutant embryo. (C) CVM-specific expression of αPS1, but not αPS2 (D), substantially rescues the CVM migration defects of αPS1 mutant embryos. (E) The αPS1PS2 transgene also shows significant rescue, although less effective than αPS1. (F) Conversely, the αPS2PS1 transgene is as little effective as αPS2. (G) Quantification of the CVM migration phenotype in Stg13 embryos of the indicated genotypes.