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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Aquat Toxicol. 2010 Jul 23;100(3):238–245. doi: 10.1016/j.aquatox.2010.07.021

Table 2.

Relative potencies (REPs) for AHR binding and human Toxic Equivalency Factors (TEFs).

HAH Chlorination pattern Beluga REPs for AHR binding Mouse REPs for AHR binding Rat REPs for AHR bindinga 2006 WHO TEFs for humans b

TCDD 2, 3, 7, 8, 1.00 1.00 1.0 1
TCDF 2, 3, 7, 8, 0.31 0.32 Not done 0.1
126 3, 3′, 4, 4′, 5 0.063 0.078 0.08 0.1
169 3, 3′, 4, 4′, 5, 5′ 0.014 0.011 Not done 0.03
77 3, 3′, 4, 4′ 0.013 0.0038 0.01 0.0001
81 3, 4, 4′, 5 0.0055 0.011 0.0004 0.0003
105 2, 3, 3′, 4, 4′ 0.00018 0.00022 0.0023 0.00003
118 2, 3′, 4, 4′, 5 0.000071 0.00011 0.0011 0.00003
156 2, 3, 3′, 4, 4′, 5 0.00033 0.0013 0.0014 0.00003
128 2, 2′, 3, 3′, 4, 4′ 0.00027 0.00025 Not done no TEF
a

calculated from IC50 reported in Bandiera et al., 1982