Fig. 5. miR-451 and 14-3-3ζ affect the activation of receptor tyrosine kinases and protein kinases.
Immunoblotting for pHer2, pEGFR, pAKT, pMAPK, and 14-3-3ζ in TamR cells treated with heregulin (HRG) for the minutes indicated after cells were transfected with A) control or 14-3-3ζ expressing polylysine-coated adenovirus or B) control or pre-miR-451 vector to overexpress miR-451. β-actin was used as a loading control.