Table 2.
Comparison of time domain analysis parameters by HIV viremia categories
| HIV negative |
HIV positive |
||||
|---|---|---|---|---|---|
| Control | Virologic suppression | Virologic nonsuppression | All HIV-positive participants | ||
| Spontaneous breathing | SDNN, ms | 68.9 (47.6, 90.5) | 53.2 (41.5, 84.2) | 63.0 (40.7, 100.2) | 60.1 (42.1, 87.1) |
| PNN50, % | 26.8 (11.9, 46.1) | 11.5 (2.1, 29.6) | 15.2 (4.4, 33.8 ) | 12.9 (2.7, 29.5)* | |
| RMSSD, ms | 48.9 (34.9, 63.8) | 37.9 (20.7, 54.0) | 42.4 (26.9, 78.6) | 41.4 (25.9, 59.5) | |
| Paced breathing | SDNN, ms | 73.3 (52.6, 82.5) | 63.8 (41.3, 83.5) | 61.9 (39.2, 88.5) | 61.9 (43.2, 85.4) |
| PNN50, % | 38.5 (24.7, 52.4) | 19.7 (2.7, 46.6) | 18.6 (9.5, 40.3) | 18.6 (3.7, 43.4) | |
| RMSSD, ms | 63.7 (40.8, 78.4) | 40.1 (29.1, 66.0) | 41.5 (31.3, 62.7) | 41.5 (30.1, 64.1)* | |
| Hand grip | SDNN, ms | 74.9 (55.3, 104.3) | 76.4 (55.8, 93.7) | 79.7 (45.1, 87.5) | 77.1 (50.9, 92.5) |
| PNN50, % | 20.1 (5.8, 28.9) | 7.6 (1.7, 21.2) | 5.8 (1.8, 34.6) | 6.7 (1.7, 22.8)* | |
| RMSSD, ms | 43.1 (30.5, 58.1) | 36.2 (20.8, 56.6) | 33.3 (23.0, 76.0) | 34.5 (23.2, 60.6) | |
| Tilt | SDNN, ms | 75.9 (58.5, 88.0) | 74.5 (55.4, 88.9) | 67.6 (40.8, 86.8) | 69.8 (51.9, 86.7) |
| PNN50, % | 16.4 (4.2, 29.2) | 5.8 (2.3, 11.0) | 3.2 (1.6, 13.2) | 5.5 (1.7, 11.0)* | |
| RMSSD, ms | 40.5 (25.4, 56.9) | 33.2 (26.6, 43.1) | 39.3 (19.9, 58.6) | 34.2 (26.6, 42.5) | |
Note: Data are presented as median (Q1, Q3), deviation for the standard deviation of normal R-R intervals (SDNN), the percentage of intervals greater than 50 ms different from its predecessor (PNN50) and the root of the mean square of successive differences (RMSSD). A Wilcoxon signed rank test was used to assess the differences between groups.
*
P < .05 compared with HIV seronegative controls.