Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Kinetic Parameters for the Reduction of trans-1-Decalone by Wild Type and Mutants of Type II Polyketide Ketoreductases (ActKR and HedKR)
| kcat (s−1) | Km (mM) | kcat/Km (s−1 mM−1) |
|
|---|---|---|---|
| ActKR | |||
| WT | 2.55 ± 0.121 | 0.790 ± 0.0850 | 3.23 ± 0.318 |
| P94L | 0.720 ± 0.193 | 0.709 ± 0.367 | 1.02 ± 0.592 |
| HedKR | |||
| WT | 0.109 ± 0.00758 | 0.591 ± 0.147 | 0.184 ± 0.0475 |
| N92L | ND | ||
| N92P | ND | ||
ND: No detectable activity
