Figure 2.

Response of other voltage-gated potassium channels to changes in extracellular potassium. (A) Representative currents from Kv1.5, Kv4.3, Kv7.1/KCNE1, and Kv11.1 channels recorded in 1 (solid) and 10 (shaded) mM [K⁺]_o as indicated. The voltage-clamp protocol (inset) was used for all the recordings. Only the duration of the step to 40 mV was varied between channels. (B) Comparison of the ratio (I_10 mM /I_1 mM) of the current amplitude measured at 40 mV in 1 and 10 mM [K⁺]_o to the theoretical ratio predicted by the GHK flux equation (dashed line). The asterisk (^∗) indicates statistically significant difference compared to the predicted ratio (p < 0.05).