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. 2011 Aug 17;101(4):847–855. doi: 10.1016/j.bpj.2011.07.013

Figure 4.

Figure 4

Bilayer-perturbing effects of long-chain alcohols. Fluorophore-loaded LUVs were made with 20 mol % of long alcohols added to the vesicle-making lipid solution. (A) Average traces without gA for the no-alcohol control, 1-dodecanol, and 1-hexadecanol (top three traces). The remaining six traces have 780 nM gA for 1-hexadecanol, 1-dodecanol, and control (middle three traces), and 816 mM ethanol (added to the aqueous LUV solution) for 1-dodecanol, control, and 1-hexadecanol (bottom three traces). (B) Fluorescence quenching rates (average ± SD, n = 4–6) for vesicles with 780 nM gA; 20 mol % of the following alcohols was added to the vesicle-making solution: nothing/control, 1-octanol, 1-decanol, 1-dodecanol, 1-tetradecanol, 1-hexadecanol, and additional DC22:1PC lipid. The asterisk indicates a significance of p < 0.01 compared with control.