Table 1.

Maximum percent drug-appropriate responding (DAR) of each test compound and effects on rate of responding at that dose.

Training Drug	Test Compound	Dose (mg/kg)	N Tes	%DAR	Rate resp/s
Propofol	Vehicle	0	8/8	15.2±12.3	0.882±0.115
Propofol	Propofol	1	8/8	35.6±17.4	1.03±0.070
Propofol	Propofol	2.5	8/8	35.3±17.1	1.122±0.129
Propofol	Propofol	5	8/8	46.6±16.4	1.225±0.126
Propofol	Propofol	10	7/7	90.7±8.3	0.992±0.067
Propofol	Chlordiazepoxide	10	5/5	64.8±21.4*	1.296±0.224
Propofol	Carisoprodol	100	5/5	59.5±24.3*	1.210±0.210
Propofol	Dizocilpine	0.1	5/5	34.1±17.0	0.376±0.216†
Propofol	Propofol + Pentylenetetrazol	10	5/5	32.2±20.4	0.941±0.273
Carisoprodol	Vehicle	0	6/6	1.2±0.8	1.171±0.192
Carisoprodol	Carisoprodol	100	6/6	99.2±0.8	1.139±0.279
Carisoprodol	Propofol	10	4/6	51.6±27.6*	0.617±0.225

N Test = number of rats which completed the first fixed ratio / total number tested. resp/s = responses per second.

^*shows values that reached the criteria for partial substitution (≥40% and <80% drug-appropriate responding and not statistically different from the training drug).

^†shows response rates different from vehicle control.