Table 3.
Multivariable-Adjusted Relations of Adiposity Measures with Log N-terminal Pro-B-Type Natriuretic Peptide After Adjustment for Selected Metabolic Traits
Independent Variables | Model including SAT | Model including VAT | ||
---|---|---|---|---|
β (SE)* | P-value | β (SE) | P-value | |
Adjusting for age, sex, SBP, anti-hypertensive treatment, and BMI | ||||
SAT† | N/A | — | N/A | |
VAT | — | −0.105 (0.031) | 0.0008 | |
Adjusting for age, sex, SBP, anti-hypertensive treatment, and waist circumference | ||||
SAT | N/A | — | N/A | |
VAT | — | −0.130 (0.033) | <0.0001 | |
Adjusting for age, sex, SBP, anti-hypertensive treatment, and metabolic syndrome | ||||
SAT | −0.036 (0.023) | 0.11 | — | N/A |
Adjusting for age, sex, SBP, anti-hypertensive treatment, BMI, and metabolic syndrome | ||||
VAT | — | −0.073 (0.033) | 0.028 | |
Adjusting for age, sex, SBP, anti-hypertensive treatment, and HOMA-IR | ||||
SAT | −0.012 (0.023) | 0.59 | — | N/A |
Adjusting for age, sex, SBP, anti-hypertensive treatment, BMI, and HOMA-IR | ||||
VAT | — | −0.057 (0.033) | 0.081 |
BMI, body mass index; HOMA-IR, homeostasis model assessment of insulin resistance; SAT, subcutaneous adipose tissue; SBP, systolic blood pressure; VAT, visceral adipose tissue.
Values represent change in log N-BNP (dependent variable) per standard deviation (SD) increase in the value of the independent continuous variables shown.
Models including SAT are not adjusted for BMI or waist circumference due to high collinearity between these variables.