Table 3. Multivariate analysis of progression of MM.
| N* | Hazard Ratio For Progression |
95% confidence interval |
P-value | ||
|---|---|---|---|---|---|
| Body mass index†: | |||||
| No TBI | |||||
| Normal | 244 | 1.00 | Poverall = 0.055 | ||
| Over-weight | 397 | 0.85 | 0.70 | 1.03 | 0.10 |
| Obese | 175 | 0.87 | 0.69 | 1.10 | 0.25 |
| Severely obese | 99 | 1.18 | 0.90 | 1.55 | 0.23 |
| TBI | |||||
| Normal | 44 | 1.00 | Poverall = 0.027 | ||
| Over-weight | 62 | 0.96 | 0.61 | 1.49 | 0.84 |
| Obese | 20 | 0.54 | 0.28 | 1.03 | 0.06 |
| Severely obese | 22 | 0.43 | 0.22 | 0.86 | 0.016 |
|
Other significant
covariates: | |||||
| Immunochemical subtype | |||||
| IgG | 576 | 1.00 | Poverall = 0.002 | ||
| IgA | 220 | 1.44 | 1.20 | 1.73 | <0.001 |
| Light chain | 168 | 1.06 | 0.86 | 1.31 | 0.58 |
| Others | 63 | 0.95 | 0.69 | 1.32 | 0.77 |
| Unknown | 36 | 1.12 | 0.75 | 1.70 | 0.58 |
| Disease status at transplant | |||||
| CR/PR | 812 | 1.00 | Poverall = 0.009 | ||
| MR/NR/SD | 227 | 1.16 | 0.97 | 1.39 | 0.10 |
| Relapse/progression | 24 | 1.84 | 1.18 | 2.86 | 0.007 |
Seven patients were excluded from the model for missing information on vital status, and 17 patients being excluded due to missing information on time to progression.
P-value for interaction between BMI and TBI = 0.0085