Table 4.
Log hormone levels and DM in HIV-infected participants*
FT Model OR (95% CI) |
FT Model: AM ONLY OR (95% CI) |
SHBG Model OR (95% CI) |
SHBG Model: AM ONLY OR (95% CI) |
|
---|---|---|---|---|
Log hormone** | 0.72 (0.37, 1.40) | 0.39 (0.17, 0.92) | 0.53 (0.26, 1.09) | 0.83 (0.35, 1.94) |
Age | 1.06 (1.00, 1.12) | 1.04 (0.97, 1.11) | 1.07 (1.01, 1.14) | 1.06 (0.99, 1.13) |
Race (Black v. other) | 2.60 (1.10, 6.11) | 2.20 (0.74, 6.50) | 3.07 (1.29, 7.27) | 2.46 (0.83, 7.27) |
Current CD4 ≥ 200 | 0.75 (0.19, 2.96) | 1.43 (0.24, 8.68) | 0.69 (0.18, 2.69) | 0.98 (0.18, 5.28) |
BMI | 1.08 (0.94, 1.24) | 1.05 (0.85, 1.29) | 1.07 (0.93, 1.23) | 1.04 (0.85, 1.28) |
HCV-infected | 1.20 (0.47, 3.08) | 1.70 (0.51, 5.63) | 1.61 (0.61, 4.23) | 2.02 (0.62, 6.60) |
Viral load ≥ 400 | 0.27 (0.09, 0.75) | 0.24 (0.07, 0.87) | 0.29 (0.10, 0.80) | 0.24 (0.07, 0.89) |
Ever stavudine therapy | 4.53 (1.91, 10.76) | 5.50 (1.77, 17.13) | 4.10 (1.74, 9.64) | 4.54 (1.55, 13.30) |
Waist circumference | 0.99 (0.94, 1.05) | 0.99 (0.93, 1.07) | 0.99 (0.94, 1.05) | 1.00 (0.93, 1.07) |
All models adjusted for log hormone, age, site, black race, BMI, HCV status, CD4, viral load, ever used d4T, and waist circumference
Odds ratio or β corresponds to each 1-log increase in either FT or SHBG