Table 2.
Correlates of severe disease, by single or multiple virus illnesses
| Correlate, n (%) | All collected samples (n = 893) | Single virus illnesses (n = 463) | Multiple virus illnesses (n = 103) | OR* (95% CI; P value) | AOR** (95% CI; P value) |
|---|---|---|---|---|---|
| Admitted to inpatient ward | 683 (76) | 347 (75) | 66 (64) | 0·60 (0·38, 0·94; 0·03) | 0·55 (0·34, 0·91; 0·02) |
| Admitted in intensive care unit | 111 (12) | 47 (10) | 2 (2) | 0·18 (0·04, 0·73; 0·02) | 0·22 (0·05, 0·91; 0·04) |
| Extended hospital stay required (>3 days) | 260 (29) | 119 (26) | 9 (9) | 0·38 (0·14, 0·57; <0·001) | 0·32 (0·15, 0·66; 0·002) |
| Supplemental oxygen required | 291 (33) | 162 (35) | 23 (22) | 0·53 (0·32, 0·88; 0·01) | 0·55 (0·33, 0·92; 0·02) |
| Assisted ventilation required | 91 (10) | 35 (8) | 1 (1) | 0·12 (0·02, 0·88; 0·04) | 0·13 (0·02, 1·00; 0·05) |
| Antibiotics used | 403 (45) | 201 (44) | 42 (41) | 0·89 (0·58, 1·38; 0·61) | 0·88 (0·56, 1·37; 0·57) |
| Bronchodilators used | 416 (47) | 60 (59) | 232 (50) | 1·44 (0·93, 2·23; 0·10) | 1·31 (0·82, 2·08; 0·24) |
| Abnormal radiographic finding*** | 202 (39) | 113 (42) | 22 (40) | 0·90 (0·50, 1·63; 0·73) | 0·87 (0·47, 1·61; 0·66) |
| Fever present within 24 hours of sample | 346 (39) | 195 (42) | 45 (44) | 1·07 (0·69, 1·64; 0·77) | 0·95 (0·60, 1·49; 0·82) |
*Crude odds ratio for multiple virus illnesses compared with single virus illnesses.
**Adjusted odds ratio, for multiple virus illnesses compared with single virus illnesses, controlling for age and presence of chronic disease.
***Among 512 chest X‐rays performed (266 in single virus illness group and 55 in multiple virus illness group).