Table 4.

Serum atorvastatin concentrations (ng ml⁻¹) at different daily doses

		Median concentration (with inquartile range) for day:
Initial daily dose (mg)	Arm	0	30	60	90
10	A	5.4 (0–10.2)	7.6 (4.8–10.5)	7.8 (3.3–11.3)	7.8 (3.8–10)
		n = 22	n = 22	n = 22	n = 22
10*	B	7.6 (5–14.8)	6.1 (2.9–10.5)	5.8 (4–12.6)	7.0 (4–8.3)
		n = 29	n = 26	n = 29	n = 22
20	A	17.6 (9.1–27)	16.7 (10–22.6)	12.3 (9.7–22.1)	14.5 (10.9–20.9)
		n = 17	n = 21	n = 24	n = 20
20*	B	11.0 (5.8–26.6)	9.8 (4.1–15.6)	11.2 (5.1–18.8)	9.5 (4.6–16.4)
		n = 22	n = 25	n = 20	n = 22
40	A	23.7 (6–30.4)	19.5 (12–45.5)	19.8 (13–35.3)	21.3 (15.4–26.1)
		n = 9	n = 9	n = 7	n = 9
40*	B	11.5 (5.7–20.7)	8.5 (7.2–12.8)	9.6 (6.8–18.5)	5.1 (2.3–8.1)
		n = 7	n = 10	n = 10	n = 8

^*Initial dose reduced by 50% after day 0 in arm B.