Table 1.
E. coli essential genes cloned.
| Gene Name | Gene Product (Target) | Gene Size (base pairs) | E. coli Clone Name |
|---|---|---|---|
| fabD | Malonyl CoA-ACP transacylase | 930 | FabD clone |
| fabI | Enol-acyl carrier protein reductase | 789 | FabI clone |
| murA | UDP-N-acetylglucosamine enolpyruvyl transferase | 1260 | MurA clone |
| murG | UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase | 1068 | MurG clone |
| prfB | Peptide chain release factor 2 | 1023 | PrfB clone |
| rplJ | 50S ribosomal protein L10 | 498 | RplJ clone |
| rpsL | 30S ribosomal protein S12 | 375 | RpsL clone |
| trpS | Tryptophanyl tRNA synthetase | 1005 | TrpS clone |