Least squares mean change from baseline in 24-h, daytime and night time ambulatory (a) SBP and (b) DBP. Hexagons represent baseline values and circles represent end point values. Dotted lines indicate the upper end of the European Society of Hypertension/European Society of Cardiology target ranges for MASBP/MADBP (24 h: 125–130/80 mm Hg; daytime: 130–135/85 mm Hg; night time: 120/70 mm Hg).20
*P⩽0.0001 versus Aml/Val/HCTZ; **P⩽0.001 versus Aml/Val/HCTZ; ***P⩽0.01 versus Aml/Val/HCTZ. Aml, amlodipine; ESH/ESC, European Society of Hypertension/European Society of Cardiology; HCTZ, hydrochlorothiazide; MADBP, mean ambulatory diastolic blood pressure; MASBP, mean ambulatory systolic blood pressure; Val, valsartan.