TABLE 1.
SIGNIFICANT KEGG PATHWAYS IN THE LIVER IDENTIFIED BY GATHER (P < 005). DIFFERENTIALLY EXPRESSED GENES IDENTIFIED BY TWO-WAY ANOVA WERE USED IN THE ANALYSIS
| Dataset | Kegg Pathway | Number of genes | P value | Bayes factor |
|---|---|---|---|---|
| Common | Mmu04060: cytokine-cytokine receptor interaction | 60 | <0.0001 | 59 |
| Mmu04620: Toll-like receptor signaling pathway | 20 | 0.01 | 12 | |
| Mmu04510: focal adhesion | 24 | 0.04 | 4 | |
| Sensitive vs. functional TLR4 resistant | Mmu04510: focal adhesion | 45 | 0.005 | 19 |
| Mmu04910: insulin signaling pathway | 31 | 0.009 | 14 | |
| Mmu04210: apoptosis | 20 | 0.02 | 7 | |
| Mmu04010: MAPK signaling pathway | 36 | 0.03 | 7 | |
| Mmu04520: adherens junction | 15 | 0.05 | 3 | |
| Sensitive vs. nonfunctional TLR4 resistant | Mmu04060: cytokine–cytokine receptor interaction | 90 | 0.003 | 22 |
| Mmu04010: MAPK signaling pathway | 86 | 0.004 | 20 | |
| Mmu04210: apoptosis | 40 | 0.01 | 13 | |
| Mmu04620: Toll-like receptor signaling pathway | 37 | 0.02 | 7 | |
| Mmu04510: focal adhesion | 64 | 0.03 | 5 | |
| Mmu04520: adherens junction | 29 | 0.04 | 5 | |
| Mmu00190: oxidative phosphorylation | 7 | 0.04 | 4 |