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. Author manuscript; available in PMC: 2011 Sep 19.
Published in final edited form as: Vet Ophthalmol. 2008 Sep;11(Suppl 1):44–50. doi: 10.1111/j.1463-5224.2008.00637.x

Figure 6.

Figure 6

(a) A photomicrograph of the unbleached H&E section: The heavily pigmented limbal melanoma is infiltrating into the cornea (green arrow), well beyond the limbus (red arrow). (Bar = 500 µm). (b) A photomicrograph of the limbal biopsy: The paraffin section is heavily bleached (potassium permanganate to remove pigment) and stained with H&E. The neoplastic cells are arranged in large aggregates within a fine fibrovascular stroma. In this section, the neoplastic cells are polygonal with abundant cytoplasm and vesiculated nuclei. The neoplastic cells exhibit mild anisocytosis, and moderate anisokaryosis. (Bar = 50 µm). (c) A photomicrograph of bleached and H&E stained section: Neoplastic melanocytes infiltrating the perivascular areas within the limbus. The neoplastic cells have spindloid (arrow head) to polygonal (arrow) morphology. (Bar = 0.25 mm). (d) A photomicrograph of bleached (potassium permanganate to remove pigment) and H&E stained section: Neoplastic melanocytes can be seen infiltrating the perivascular areas within the choroid. The neoplastic cells have spindloid to polygonal morphology. (Bar = 0.25 mm).