Table 1.

Content Overlap of a Toxicology Elective with Pharmacology III and Pharmacotherapy II Courses

Toxicology Elective Content	Content Overlap With:
	Pharmacology III	Pharmacotherapy II
Introduction to toxicology and risk assessment, introduction to emergency management of toxicological emergencies		√
Routes of toxic exposures and classification of effects (local vs. systemic, reversible vs. irreversible, etc), dose-response relationships		√
Target organ toxicity		√
Toxicokinetics and Toxicity testing using in vitro and in vivo models
Principles of chemical carcinogenesis and mutagenesis
Principles of reproductive and developmental toxicology
Principles of radiation toxicology; historic radiation-related accidents
Toxicity of therapeutic agents: sedative/hypnotics, anticholinergic drugs, and neuroleptic drugs	√	√
Toxicity of therapeutic agents: acetaminophen, salicylates, NSAIDs, and steroids		√
Toxicity of therapeutic agents: cardiovascular drugs		√
Toxicity of potential drugs of abuse: opioids and sympathomimetics	√	√
Toxicity of potential drugs of abuse: hallucinogenic agents	√
Toxicity of vitamins, herbs, and alcohols		√
Toxicity of metals		√
Agents of biological and chemical warfare		√

Abbreviations: NSAIDS: nonsteroidal anti-inflammatory drugs