Table 3.
Effects of the essential oils from C. sempervirens var. horizontalis, C. sempervirens var. pyramidalis, J. communis, J. excelsa, J. foetidissima, J. oxycedrus, and J. phoenicea on circular excision wound model.
Material | Wound area ± SEM (contraction %) | ||||||
---|---|---|---|---|---|---|---|
0 | 2 | 4 | 6 | 8 | 10 | 12 | |
Vehicle | 19.55 ± 2.09 | 17.98 ± 2.20 (2.55) |
16.54 ± 2.11 — |
14.89 ± 1.95 — |
9.55 ± 1.56 (9.51) |
6.31± 1.16 (8.42) |
2.97 ± 0.87 (5.41) |
Negative Control | 19.43 ± 2.15 | 18.45 ± 2.23 | 16.42 ± 2.17 | 14.72 ± 1.91 | 10.51 ± 1.75 | 6.89 ± 1.23 | 3.14 ± 1.49 |
C. sempervirens var. horizontalis | 19.40 ± 2.13 | 17.56 ± 1.40 (2.34) |
16.02 ± 1.50 (3.14) |
14.91 ± 1.62 — |
9.57 ± 1.40 — |
5.86 ± 1.32 (7.13) |
3.56 ± 0.69 — |
C. sempervirens var. pyramidalis | 20.03 ± 2.12 | 17.90 ± 1.91 (0.44) |
16.69 ± 1.92 — |
14.92 ± 1.60 — |
8.84 ± 1.67 (7.43) |
7.08 ± 1.12 — |
2.59 ± 0.84 (12.79) |
J. communis subsp. nana Syme. | 19.55 ± 2.22 | 17.81 ± 1.81 (5.56) |
16.75 ± 1.80 — |
15.16 ± 1.87 — |
9.57 ± 1.74 — |
6.02 ± 0.99 (4.60) |
3.04 ± 0.89 — |
J. excelsa | 19.50 ± 2.16 | 14.99 ± 1.78 (16.63) |
13.24 ± 2.09 (19.95) |
11.26 ± 1.70 (24.38) |
7.39 ± 1.58 (22.62) |
5.47 ± 1.07 (13.31) |
2.44 ± 0.90 (17.85) |
J. foetidissima | 19.96 ± 2.51 | 16.16 ± 1.89 (10.12) |
14.02 ± 1.78 (15.24) |
13.49 ± 1.71 (9.40) |
9.09 ± 1.54 (4.82) |
6.10 ± 1.27 (3.33) |
2.49 ± 1.05 (16.16) |
J. oxycedrus subsp. oxycedrus | 19.41 ± 2.08 | 17.51 ± 1.92 (2.61) |
16.02 ± 1.70 (6.05) |
12.62 ± 1.63 (15.25) |
6.03 ± 1.03 (36.86)* |
3.85 ± 0.96 (38.99)* |
1.69 ± 0.60 (43.10)* |
J. phoenicea | 19.59 ± 2.19 | 16.46 ± 2.54 (8.45) |
14.02 ± 1.96 (15.24) |
11.97 ± 1.86 (19.61) |
7.44 ± 1.39 (22.09) |
4.21 ± 1.28 (33.28)* |
1.76 ± 0.61 (40.74)* |
Madecassol | 19.68 ± 2.03 | 14.46 ± 1.83 (19.58) |
11.77 ± 1.45 (28.84) |
8.76 ± 1.21 (41.17)** |
4.74 ± 0.89 (50.37)** |
2.12 ± 0.31 (66.40)*** |
0.00 ± 0.00 (100.00)*** |
* P < 0.05; ** P < 0.01; *** P < 0.001; SEM: standard error of the mean.
Percentage of contraction values: vehicle group was compared to negative control group; the oils and the reference material were compared to vehicle group.